by Sequoia Capital
Join us as we train our neural nets on the theme of the century: AI. Sonya Huang, Pat Grady and more Sequoia Capital partners host conversations with leading AI builders and researchers to ask critical questions and develop a deeper understanding of the evolving technologies—and their implications for technology, business and society. The content of this podcast does not constitute investment advice, an offer to provide investment advisory services, or an offer to sell or solicitation of an offer to buy an interest in any investment fund.
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Publishing Since
6/5/2024
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April 15, 2025
Josephine Chen and Pat Grady interview Patrick Hsu, co-founder of Arc Institute, about leveraging AI to build an app store for biology with Evo 2, enabling diverse biological applications.
April 8, 2025
Amjad Masad set out more than a decade ago to pursue the dream of unleashing 1B software creators around the world. With millions of Replit users pre-ChatGPT, that vision was already becoming a reality. Turbocharged by LLMs, the vision of enabling anyone to code—from 12-year-olds in India to knowledge workers in the U.S.—seems less and less radical. In this episode, Amjad explains how an explosion in the developer population could change the economy, society and more. He also discusses his early days programming in Jordan, his unique management approach and what AI will mean for the global economy. Hosted by David Cahn and Sonya Huang, Sequoia Capital Mentioned in this episode: On the Naturalness of Software: 2012 paper on applying NLP to code Attention Is All You Need: Seminal 2017 paper on transformers I Am a Strange Loop: 2007 follow up to Douglas Hofstadter’s 1979 classic Gödel, Escher, Bach that explores how self-referential systems can describe minds On Lisp: Paul Graham’s 1993 book on the original programming language of AI
April 1, 2025
Christopher O’Donnell believes the fundamental problems with CRM—incomplete data, complex workflows, siloed work products and the fear of leads falling through the cracks—can finally be solved through AI. Founder of Day.ai and former Chief Product Officer of HubSpot, Christopher explains how his team is building a system that automatically captures the full context of customer relationships while giving users transparency and control. He shares lessons from building HubSpot’s CRM and why he’s taking a deliberate approach to product development despite the pressure to scale quickly in the AI era. Hosted by Pat Grady, Sequoia Capital Mentioned in this episode: The Innovator's Dilemma: Classic book by Clay Christensen (referenced regarding HubSpot's second S-curve strategy) Hubspot CRM: The only product to successfully challenge Salesforce’s dominance in the CRM category From Super Mario Brothers to Elden Ring: Analogy to what an AI-powered CRM experience can be through comparison of video games launched in 1985 vs 2022 Punk’d: Hidden camera–practical joke reality television series that premiered on MTV in 2003, created by Ashton Kutcher and Jason Goldberg Slow is smooth and smooth is fast: SEALs-derived concept mentioned regarding product development) Aga stove (highlighted as extraordinary product design example)
Conviction
a16z
Sequoia Capital
swyx + Alessio
Y Combinator
Andreessen Horowitz
BG2Pod
Harry Stebbings
Dwarkesh Patel
by Redpoint Ventures
Jason Calacanis
Jessica Livingston
Machine Learning Street Talk (MLST)
SaaStr
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