by SelfDecode
Unlock the secrets of your DNA and optimize your health with The Joe Cohen Show. Join Joe, biohacker and founder of SelfDecode, as he interviews world-class health experts and shares cutting-edge research and strategies for biohacking your body and brain. From functional medicine tips and supplement recommendations to longevity and performance optimization, each episode is packed with insights to help you achieve your health goals. Whether you're interested in genetics, biohacking, alternative health, or simply improving your overall wellness, this podcast has something for you. Subscribe now!
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🇺🇲
Publishing Since
9/26/2022
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April 18, 2025
<p>In this eye-opening episode of The Joe Cohen Show, Joe sits down with microbiologist and biotech entrepreneur Kiran Krishnan to dismantle the myths and marketing hype surrounding microbiome testing. </p><p>Drawing parallels between the DNA and microbiome industries, they expose the scientific shortcuts, technological flaws, and misleading health claims being sold to consumers.</p><p>Krishnan, the mind behind one of the few microbiome platforms used in published research, breaks down what a legitimate test looks like and why most tests on the market fall short, sometimes by as much as 70% in accuracy. </p><p>The conversation also explores probiotics in depth, why strain specificity matters, and how consumers can make more informed decisions when navigating this complex and evolving space.</p><p>Whether you’re a health professional or someone trying to optimize your gut, this episode will help you separate science from sales.</p><p>📌 Topics covered: microbiome testing technology, bioinformatics, probiotic strains, sequencing methods, red flags in wellness tech</p><p>- Check out SelfDecode: https://selfdecode.com/</p><p>- Join Joe’s online community: https://thejoecohenshow.com/ </p><p><br></p><p>(00:00) - Introduction to the Joe Cohen Show</p><p>(00:16) - Meet Kiran Krishnan</p><p>(01:07) - Understanding Microbiome Testing</p><p>(03:01) - The Importance of Whole Genome Sequencing</p><p>(04:48) - Challenges in Microbiome and Genetic Testing</p><p>(05:42) - Critique of 16S Ribosomal RNA Sequencing</p><p>(11:58) - Issues with Viome and Other Testing Companies</p><p>(21:14) - Complexities of Microbiome Mapping</p><p>(23:27) - Validating Microbiome Tests</p><p>(27:04) - The Future of Microbiome Technology</p><p>(28:10) - Advancements in Genome Sequencing</p><p>(29:18) - Challenges in Microbiome Analysis</p><p>(30:40) - Economic Realities of Sequencing</p><p>(31:57) - Company Strategies and Ethics</p><p>(33:49) - Benefits of Microbiome Testing</p><p>(35:12) - Probiotics and Gut Health</p><p>(38:20) - Top Probiotic Strains</p><p>(43:00) - Importance of Specific Strains</p><p>(52:52) - Concluding Thoughts on Probiotics</p>
April 15, 2025
<p>Most genetic testing companies promise personalized health insights, but their reports barely scratch the surface, often analyzing just a handful of genetic variants. </p><p>In this episode, Joe Cohen shares what happened when the SelfDecode team took a close look at dozens of these reports to understand how and why they fall short and what it actually takes to do it right.</p><p>He shares how SelfDecode analyzes hundreds of thousands (sometimes millions) of variants per report, uses advanced technology to generate more accurate results, and integrates labs and lifestyle data to deliver truly actionable recommendations. </p><p>If you've ever wondered whether your DNA test was worth the money, this episode is a must-listen.</p><p>- Check out the SelfDecode Report Shop: https://selfdecode.com/shop/</p><p>- Check out SelfDecode: https://selfdecode.com/</p><p>- Join Joe’s online community: https://thejoecohenshow.com/ </p><p>(00:00) - Introduction</p><p>(00:16) - Overview of Genetic Reports</p><p>(01:26) - Competitor Analysis and 100X Series</p><p>(02:34) - Detailed Breakdown of Genetic Reports</p><p>(03:27) - Recreating Competitor Reports</p><p>(08:57) - Final Thoughts</p>
April 11, 2025
<p>In this episode, Joe Cohen talks with Mark Notton, founder of Revive DNA, about how your DNA can shape your sleep, energy, and long-term health.</p><p>After helping his wife recover from a chronic autoimmune condition using a personalized nutrition approach, Mark left his executive career at Samsung to launch a health tech company.</p><p>Now, Revive DNA is making science-backed, DNA-driven wellness accessible to more people with support from major institutions and powered by OmicsEdge technology.</p><p>Tune in for a deep dive into the future of personalized health and what most programs are still getting wrong.</p><p><br></p><p>- Check out SelfDecode: https://selfdecode.com/</p><p>- Join Joe’s online community: https://thejoecohenshow.com/ </p><p><br></p><p>Timestamps:</p><p>(00:00) - Introduction</p><p>(00:16) - Meet Mark Noten: Founder of Revive DNA</p><p>(01:06) - Mark's Journey into the Health Space</p><p>(02:09) - A Personal Health Crisis: Mark's Wife's Story</p><p>(04:40) - The Role of DNA in Health and Nutrition</p><p>(06:44) - Revive DNA: Technology and Partnerships</p><p>(11:53) - Revive DNA App: Features and Benefits</p><p>(19:31) - Upcoming Sleep Study with Samsung</p><p>(28:43) - Future Directions and Closing Remarks</p>
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